How to Make Blood Smears

How to Make Blood Smears

Blood smears are the most important part of great CBC results. Smears should preferably be made without any anticoagulant at the time of sample acquisition. If you must delay, please aim to make smears within a few minutes of the blood being placed in the blood tube. If you wait and have us make the smear on arrival, the blood has lots of artifacts including smudge cells and degenerated WBC and RBC.

While some advocate cover slip smears, we actually find those that are submitted to our lab are quite thick and the results are not valid. For best results, we recommend the use of the push method which can be done using two slides. Be gentle! Don’t place too much blood on the slide! Check out the video below. A little practice makes perfect. Thanks!

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