News : 2014

New Publication on Aspergillosis

Check out our collaborators’ new publication on diagnostic tools for the detection of aspergillosis — adult and juvenile falcons were experimentally infected with different dosages of Aspergillus fumigatus. Blood samples were analyzed on day 0 and day 28 for antibody and galactomannan and changes in plasma proteins by protein electrophoresis, haptoglobin, and serum amyloid A.

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New Publication on Reference Intervals

Dr. Carolyn Cray authored a chapter in the upcoming issue of Veterinary Clinics of North America: Exotic Animal Practice entitled, “Reference intervals in avian and exotic hematology”. In this chapter, she discusses the difficulties in applying the current ASVCP guidelines for reference interval generation to avian and exotic species. Sources of biological variation and pre analytical error are reviewed. The use of the indirect estimation of reference intervals and the index of individuality analysis in avian species is also summarized.

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December Holiday Schedule

The laboratory will be closed December 25 and January 1. The lab will be open on December 24 and 26 as well as December 31 and January 2. Please contact the laboratory at (800)596-7390 or compathlab@med.miami.edu with any questions.

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Thanksgiving Laboratory Schedule

The lab will be closed on Thursday, November 27 but will be open to receive specimens on November 24 to 26 and on Friday, November 28. Please contact the laboratory at (800)596-7390 or compathlab@med.miami.edu with any questions.

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Thanks for a Great AAZV/AEMV/ARAV Conference

The Avian & Wildlife Laboratory was pleased to have an opportunity to sponsor sessions for the AEMV and ARAV again this year as well as host a booth in the exhibit hall. Dr. Cray presented two lectures including a presentation of serodiagnostic and acute phase protein testing for Encephalitozoon cuniculi in rabbits and the applications of protein and cholesterol electrophoresis in the cownose ray. We were also pleased to collaborate in other studies which were presented at the meeting. Thanks again for your continued support of our clinical pathology laboratory service. This greatly aids in the support of our research mission.

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New Publications on Lipid Levels in Psittacines

Two new publications on lipid levels in psittacines have been published in the current issue of the Journal of Avian Medicine & Surgery. Dr. Beaufrere and colleagues published, “Association of Plasma Lipid Levels with Atherosclerosis in Psittaciformes” and Dr. Ravich and colleagues published “Lipid Panel Reference Intervals for Amazon Parrots (Amazona species)”. The Avian & Wildlife Laboratory was pleased to collaborate in both of these studies.

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Your Continuing Contribution to Avian Medicine

More than twenty years ago, the Division of Comparative Pathology established a section of our laboratory with the goal of providing a strong avian, exotic, and wildlife diagnostic test array to meet the changing needs of our veterinary clients. The response of the veterinary community has been exceptional. The wealth of unique samples that have been submitted to our laboratory as well as funds derived from performing the clinical tests has combined to provide numerous opportunities to perform valuable research studies and further the field of veterinary medicine. Your contributions have been invaluable.

Our commitment to specialized veterinary medicine:

88 presentations at national and international meetings
91 journal articles
5 book chapters

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Time to Update Your Rabbit and Ferret Bloodwork

Acute phase protein (APP) testing has become part of the standard of care in many areas in Europe. A wealth of literature has well demonstrated the sensitivity of APP testing over routine complete blood counts in companion animals and large animals. In mammalian species, it outperforms protein electrophoresis. APP testing is routinely used in wellness exams and as a valuable prognostic test. Major APP rise rapidly after insult – often within 24 hours and can have a 10-100 fold increase in magnitude. As the cause of inflammation is addressed, rapid decreases in these markers also occur. Increases have been shown to increase with inflammatory diseases, infection, neoplasia, trauma, and stress. You can see more about APP and our research studies at the Acute Phase Protein Laboratory.

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New Publication on Hemoglobin Binding Protein in Loggerhead Turtles

This marks the first report of implementation of an assay for hemoglobin binding protein in loggerhead turtles. Eighteen samples reflecting pre and post rehabilitation status were examined by this assay and plasma protein electrophoresis. Significant differences in all analytes were observed between these timepoints and, notably, hemoglobin binding protein levels were found to increase during the rehabilitation period. These results indicate that this assay may serve as a useful tool in assessing the health of sea turtles. As all 7 free ranging sea turtle species have either endangered or threatened status, this new assay may have relevance in the study of wild populations and in monitoring the health status of turtles under human care.

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New Publication on Acute Phase Proteins in Elephants

A new paper is available as early in press in the Journal of Veterinary Diagnostic Investigation which details the first reference intervals for protein electrophoresis and acute phase proteins for the Asian elephant. Results include values from 35 clinically normal animals and 9 animals with clinical problems including pododermatitis, infected tusk, and a traumatic knee injury. While significant differences in some electrophoretic values were present, the specific assay for serum amyloid A was especially sensitive for underlying inflammatory processes offering more than a 5 to 10 fold increase in levels. This acute phase protein should be considered as a health monitoring and prognostic tool in this species.

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