News : 2013

New Publications on Acute Phase Proteins in Exotic Animals

Acute phase proteins (APP) were first identified in the early 1900’s as early reactants to infectious disease. They are now understood to be an integral part of the acute phase response which is the cornerstone of innate immunity. APP have been shown to be valuable biomarkers as increases can occur with inflammation, infection, neoplasia, stress, and trauma. All animals – from fish to mammals – have demonstrable APP but the type of major APP differs by species. While the primary application of these proteins in a clinical setting is prognostication, studies in animals have demonstrated relevance to diagnosis and detection and monitoring for subclinical disease. APP have been well documented in laboratory, companion, and large animals. It has only been recently that investigations have been initiated in avian, exotic, and wildlife species.

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Holiday Schedule

The laboratory will be closed on December 25 and January 1. The lab will be open but with limited staffing on November 29 and January 20. Please call us with any questions or concerns regarding testing and shipping over the holidays.

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New Publication on Alternative Method to Generate Reference Intervals

In human and veterinary medicine, reference intervals for hematologic and biochemical testing are an essential part in test interpretation, the generation of a diagnosis, and prognostication. Superior reference intervals are generated from a large sample size of clinically normal individuals. This is sample set is often greater than 120 data points. In veterinary medicine, and perhaps especially so in avian medicine, it is particularly difficult to obtain specimens from that number of individuals or even a lesser number of 40 individuals for which a different method of statistical analysis can be used. Time and cost factors are major considerations as well as access to the appropriate number of birds that have a complete health history. In our current study, we have examined the use of indirect sampling method for the generation of reference intervals in avian species.

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APP Expression During EEHV Viremia in Asian Elephants

The September issue of the Journal of Zoo and Wildlife Medicine features a study of acute phase protein expression in Asian elephants during elephant endotheliotropic herpesvirus-1 viremia in Asian elephants (Elephas maximus). The study was conducted in the Acute Phase Protein Laboratory at the University of Miami by Dr. Carolyn Cray. Collaborating investigators at the Baylor College of Medicine contributed valuable samples for analysis from elephants in differing periods of infection. The data indicated that EEHV-1 infection does result in acute inflammation and that APP levels may aid in the health monitoring of this species.

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UMiami Proudly Sponsors Sessions at Joint AEMV/ARAV Conference

The Avian & Wildlife Laboratory is pleased to have the opportunity to sponsor sessions at the upcoming Joint AEMV/ARAV Conference to be held in Indianapolis from September 14-19. As a Bronze Level sponsor, we are hosting the AEMV Pathology Session and the ARAV Infectious Disease Session. The joint program looks to be excellent once again this year. Unfortunately, this year Dr. Carolyn Cray will not be joining the meeting participants as she was asked to lecture about acute phase proteins on behalf of the European Society of Veterinary Clinical Pathology at the 23rd Congress of the European College of Veterinary Internal Medicine in Liverpool. Check back for her summary of this meeting later this month.

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Exotic Species Cancer Research Alliance

The Exotic Species Cancer Research Alliance is asking for your help in understanding various animal models of cancer and building information that may help to treat cancer in animals and humans. This group was represented at the recent AAV meeting and will also be at the upcoming AAZV meeting. To learn more, go to their website. The site has a short survey on cases of avian squamous cell carcinoma. Show your support in helping pave this two-way street between human and veterinary medicine.

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Congratulations to Dr. Susan Clubb, Recognized with the T.J. Lafeber Award

The many contributions of Dr. Susan Clubb were recognized this year with the T.J. Lafeber Avian Practitioner Award. This annual award is presented to a outstanding practitioner who has readily demonstrated clinical excellence, innovation, promotion of the profession of avian veterinarian, contributions to avian research, and caring to their avian patients and clients.

Our laboratory has been fortunate to have worked with Dr. Clubb for nearly 20 years. While serving as an adjunct professor in Comparative Pathology at the University of Miami, Dr. Clubb has collaborated with Dr. Carolyn Cray on 18 publications and presentations. She has been a valuable colleague and advisor to the Avian & Wildlife Laboratory. We congratulate her on this distinct honor and look forward to many more years of research.

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See You at AAV in Jacksonville

We are pleased again to sponsor a session at the annual AAV meeting. This year we have the honor of sponsoring the Disease Syndromes session held on the opening day, August 4. Dr. Carolyn Cray will be presenting her current work entitled, “Alternative Antigen Detection Testing for Avian Aspergillosis”. She is also co-author on 2 other presentations including a poster presentation entitled, “Monoclonal Bands Observed in Protein Electrophoresis of Plasma in Avian Samples” with Drs. Clubb, Lennox, and Romagnano.

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Your Continuing Contribution to Veterinary Medicine

Twenty years ago, the Division of Comparative Pathology established a section of our laboratory with the goal of providing a strong avian, exotic, and wildlife diagnostic test array to meet the changing needs of our veterinary clients. The response of the veterinary community has been exceptional. The wealth of unique samples that have been submitted to our laboratory as well as funds derived from performing the clinical tests has combined to provide numerous opportunities to perform valuable research studies and further the field of veterinary medicine. Your contributions have been invaluable.

Our commitment to specialized veterinary medicine:

79 presentations at national and international meetings
73 journal articles
4 book chapters

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New Study on Atherosclerosis in Quaker Parrots

The Avian & Wildlife Laboratory was pleased to collaborate with Dr. Hugues Beaufrere and his colleagues at Lousiana State University as well as Dr. Susan Clubb on a study recently published in Veterinary Pathology. Entitled, “Experimental Diet-Induced Atherosclerosis in Quaker Parrots (Myiopsitta monachus), Dr. Beaufrere studied the effects of an atherogenic diet composed on 1% cholesterol for 2 to 8 months. Significant atherosclerotic lesions were observed as early as 2 months. Plasma cholesterol and low-density lipoprotein were observed to increase over time. This dyslipdemia developed quickly and plateaued at 3-4 months. The complete study can be viewed in the journal’s OnlineFirst section.

We also congratule Dr. Beaufrere on his selection as recipient of the 2013 Donald W. Zantop Emerging Leader Award!

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