News : 2016 : August

Acute Phase Proteins in the Przewalski’s Horse

The laboratory was pleased to have the opportunity to collaborate with the Smithsonian’s National Zoological Park on a study of acute phase protein expression in a Przewalsk’s horse (Equus ferus przewalski). In this study, the horse presented with an aspiration pneumonia which did not resolve over a two month period. Minimal changes were observed in hematologic analyses. Protein electrophoresis, serum amyloid A (SAA) and surfactant protein D serum concentrations were found to more accurately reflect the severity of disease.

The Acute Phase Protein Laboratory had previously worked to validate SAA testing in domestic horses and the Grant’s zebra. Acute phase proteins have been shown to be valuable markers of inflammation in these and other species. Many thanks to all of our collaborators. More information on this study can be seen in the Journal of Zoo and Wildlife Medicine 47(2):654-658, 2016.