News : 2012 : October

New Publication on Acute Phase Proteins

Dr. Carolyn Cray has authored an extensive review paper entitled, “Acute Phase Proteins in Animals”. Published in the current issue of Progress in Molecular Biology and Translational Science, this paper provides an excellent summary of the acute phase response. The biology of each major acute phase protein is discussed as well as their clinical value. Lastly, an extensive review of the publications on this subject is provided by species. This paper should serve as a key reference to all interested in this growing field of biomarkers of inflammation. If you would like a copy of this paper, please contact the laboratory (PMBTS, 105:113-150, 2011).

Details included in this paper include the clinical value of acute phase proteins in diagnosis, prognosis, and detection of subclinical disease. These are key attributes of these biomarkers in their ready application to veterinary medicine. An extensive summary is provided regarding the use of serum amyloid A (SAA) testing in horses. Both published and new studies conducted in the Acute Phase Protein Laboratory are presented in the section on acute phase proteins in Avian, Exotic, & Wildlife species.

The application of acute phase proteins to veterinary medicine is an active area of research in our laboratory. Questions and potential collaborative projects can be sent to Dr. Cray’s attention at ccray@med.miami.edu.